Assay Detail
Binding
CHEMBL5042376
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Binding affinity to rat adenosine A3 receptor measured by radioligand binding assay
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Selective A<sub>3</sub> Adenosine Receptor Antagonist Radioligand for Human and Rodent Species.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 9.39 | 9.77 |
| Ki | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27376 | — | — | 1 | 9.77 |
| CHEMBL133566 | — | — | 1 | 9.00 |
| CHEMBL302765 | — | — | 1 | - |
| CHEMBL1625681 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27376 | — | Kd | = | 0.17 | nM | 9.77 |
| CHEMBL133566 | — | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL302765 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1625681 | — | Ki | > | 10000.0 | nM | - |