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Assay Detail

CHEMBL5045821

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PI5P4Kalpha (unknown origin) by bioluminescent assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Publication

Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode.
Boffey HK, Rooney TPC, Willems HMG, Edwards S, Green C, Howard T, Ogg D, Romero T, Scott DE, Winpenny D, Duce J, Skidmore J, Clarke JH, Andrews SP.
J Med Chem (2022) 65 : 3359 -3370
PubMed 35148092 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4455633 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4455633 IC50 = 2000.0 nM 5.70