Assay Detail
Functional
CHEMBL5048136
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Cytotoxicity against human U-87 MG cells assessed as cell viability using raw interpretation method
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-87MG ATCC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cyclotides Chemosensitize Glioblastoma Cells to Temozolomide.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.31 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1801036 | CYCLOVIOLACIN O13 | — | 1 | 5.47 |
| CHEMBL5090055 | — | — | 1 | 5.42 |
| CHEMBL4285275 | — | — | 1 | 5.25 |
| CHEMBL4211294 | — | — | 1 | 5.10 |
| CHEMBL810 | TEMOZOLOMIDE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1801036 | CYCLOVIOLACIN O13 | IC50 | = | 3360.0 | nM | 5.47 |
| CHEMBL5090055 | — | IC50 | = | 3760.0 | nM | 5.42 |
| CHEMBL4285275 | — | IC50 | = | 5660.0 | nM | 5.25 |
| CHEMBL4211294 | — | IC50 | = | 7970.0 | nM | 5.10 |
| CHEMBL810 | TEMOZOLOMIDE | IC50 | = | 3186000.0 | nM | - |