Assay Detail
Binding
CHEMBL5050323
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of BRD4-BD2 (unknown origin) assessed as dissociation constant by TR-FRET method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
CRCM5484: A BET-BDII Selective Compound with Differential Anti-leukemic Drug Modulation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 8.80 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4297454 | ABBV-744 | 1.0 | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4297454 | ABBV-744 | Kd | = | 1.6 | nM | 8.80 |