Assay Detail
Binding
CHEMBL5054019
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]8-OH-DAPT from human recombinant 5-HT1A receptor expressed in COS7 cells measured after 60 to 90 mins by radioligand completion assay relative to control
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | COS7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Activity of <i>Mitragyna speciosa</i> ("Kratom") Alkaloids at Serotonin Receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.62 | 9.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8412 | IPSAPIRONE | 2.0 | 1 | 9.62 |
| CHEMBL31354 | WAY-100,635 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8412 | IPSAPIRONE | Ki | = | 0.24 | nM | 9.62 |
| CHEMBL31354 | WAY-100,635 | Ki | - | — | - |