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Assay Detail

CHEMBL5058438

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitumor activity against human wild type NCI-N87 cells assessed as cell numbers measured after 48 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NCI-N87
Confidence 1 — Organism
Curated By Autocuration

Target

NCI-N87 (CHEMBL614197)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer.
Luxenburger A, Bougen-Zhukov N, Fraser MG, Beetham H, Harris LD, Schmidt D, Cameron SA, Guilford PJ, Evans GB.
J Med Chem (2021) 64 : 18114 -18142
PubMed 34878770 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.07 5.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5074766 1 5.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5074766 EC50 = 8500.0 nM 5.07