Assay Detail
Binding
CHEMBL5059567
Review assay metadata, readout intent, target linkage, and publication context from the same page.
NanoBRET assay (FKBP51-NLuc) (FKBP5)
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peptidyl-prolyl cis-trans isomerase FKBP5 (CHEMBL2052031) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe SAFit2
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.31 | 6.31 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | 200 nM of tracer 2c |
| Assay publication | Assay publication | - | — | PMID: 33887102 |
| Target protein type | Target protein type | - | — | HEK293Tcells stably over-expressing FKBP51-NLuc |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3623630 | — | — | 1 | 6.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3623630 | — | IC50 | = | 493.0 | nM | 6.31 |