Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5096469

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human wild type AK expressed in Escherichia coli using [2,8- 3H]-Ado and ATP as substrate by radiometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Adenosine kinase (CHEMBL3589)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer's Disease Multitarget Drug Discovery?
De Simone A, Tumiatti V, Andrisano V, Milelli A.
J Med Chem (2021) 64 : 26 -41
PubMed 33346659 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.92 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL223769 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL223769 IC50 = 1200.0 nM 5.92