Assay Detail
Binding
CHEMBL5096571
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NUAK1 in HEK293 cells assessed as effect on MYPT1 phosphorylation at Ser445 incubated for 3 mins by immunoblotting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development and Therapeutic Potential of NUAKs Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.00 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5190521 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5190521 | — | IC50 | = | 10000.0 | nM | 5.00 |