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Assay Detail

CHEMBL5096609

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity at CB2 receptor (unknown origin) expressed in CHO cell membranes assessed as increase in [35S]GTPgammaS binding incubated for 60 mins by liquid scintillation spectrometry analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CHO
Subcellular Membrane
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 2 (CHEMBL253)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Phytocannabinoid Pharmacology: Medicinal Properties of <i>Cannabis sativa</i> Constituents Aside from the "Big Two".
Sampson PB.
J Nat Prod (2021) 84 : 142 -160
PubMed 33356248 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.01 7.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2387541 TETRAHYDROCANNABIVARIN 2.0 1 7.01

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2387541 TETRAHYDROCANNABIVARIN EC50 = 98.0 nM 7.01