Assay Detail
Binding
CHEMBL5096636
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at TRPA1 (unknown origin) activation
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transient receptor potential cation channel subfamily A member 1 (CHEMBL6007) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Phytocannabinoid Pharmacology: Medicinal Properties of <i>Cannabis sativa</i> Constituents Aside from the "Big Two".
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.48 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL422704 | CANNABICHROMENE | — | 1 | 7.05 |
| CHEMBL74415 | CANNABINOL | 3.0 | 1 | 6.75 |
| CHEMBL4170268 | — | — | 1 | 6.70 |
| CHEMBL2387742 | CANNABIDIVARIN | 2.0 | 1 | 6.38 |
| CHEMBL497318 | CANNABIGEROL | 2.0 | 1 | 6.16 |
| CHEMBL2387541 | TETRAHYDROCANNABIVARIN | 2.0 | 1 | 5.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL422704 | CANNABICHROMENE | EC50 | = | 90.0 | nM | 7.05 |
| CHEMBL74415 | CANNABINOL | EC50 | = | 180.0 | nM | 6.75 |
| CHEMBL4170268 | — | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL2387742 | CANNABIDIVARIN | EC50 | = | 420.0 | nM | 6.38 |
| CHEMBL497318 | CANNABIGEROL | EC50 | = | 700.0 | nM | 6.16 |
| CHEMBL2387541 | TETRAHYDROCANNABIVARIN | EC50 | = | 1500.0 | nM | 5.82 |