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Assay Detail

CHEMBL5096730

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to rat STING T230I A239V mutant assessed as dissociation constant by isothermal titration calorimetry assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

STING, a promising target for small molecular immune modulator: A review.
Liu Y, Lu X, Qin N, Qiao Y, Xing S, Liu W, Feng F, Liu Z, Sun H.
Eur J Med Chem (2021) 211 : 113113 -113113
PubMed 33360799 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.13 5.13

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1569545 CRIDANIMOD 3.0 1 5.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1569545 CRIDANIMOD Kd = 7400.0 nM 5.13