Assay Detail
Binding
CHEMBL5096763
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Binding affinity to human recombinant PD-L1 by surface plasmon resonance assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advance of peptide-based molecules and nonpeptidic small-molecules modulating PD-1/PD-L1 protein-protein interaction or targeting PD-L1 protein degradation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.08 | 6.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4514311 | — | — | 1 | 6.29 |
| CHEMBL4583803 | — | — | 1 | 5.86 |
| CHEMBL4530490 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4514311 | — | Kd | = | 510.0 | nM | 6.29 |
| CHEMBL4583803 | — | Kd | = | 1380.0 | nM | 5.86 |
| CHEMBL4530490 | — | Kd | = | 94.0 | nM | - |