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Assay Detail

CHEMBL5096841

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of full length human recombinant HDAC10 incubated for 30 to 60 mins by HDAC-Glo I/II assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Polyamine deacetylase HDAC10 (CHEMBL5103)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A Review of Progress in Histone Deacetylase 6 Inhibitors Research: Structural Specificity and Functional Diversity.
Zhang XH, Qin-Ma, Wu HP, Khamis MY, Li YH, Ma LY, Liu HM.
J Med Chem (2021) 64 : 1362 -1391
PubMed 33523672 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.43 6.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5195946 1 6.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5195946 IC50 = 375.0 nM 6.43