Assay Detail
Functional
CHEMBL5096957
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Reversal of HIV-1 latency in human J-Lat 9.2 cells assessed as increase in GFP expression incubated for 24 hrs by flow cytometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | J-Lat 9.2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
HIV latency reversal agents: A potential path for functional cure?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.35 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL170518 | PROSTRATIN | — | 1 | 7.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL170518 | PROSTRATIN | EC50 | = | 45.0 | nM | 7.35 |