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Assay Detail

CHEMBL5097124

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human BuchE using butyrylthiocholine iodide as substrate by Ellman colorimetric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cholinesterase (CHEMBL1914)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease.
Singh YP, Rai H, Singh G, Singh GK, Mishra S, Kumar S, Srikrishna S, Modi G.
Eur J Med Chem (2021) 215 : 113278 -113278
PubMed 33662757 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.64 6.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5197518 1 6.68
CHEMBL5190569 1 6.59

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5197518 IC50 = 210.0 nM 6.68
CHEMBL5190569 IC50 = 255.0 nM 6.59