Assay Detail
Binding
CHEMBL5097314
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to N-terminal his6-tagged human recombinant Haspin (470 to 798 residues) assessed as dissociation constant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase haspin (CHEMBL1075163) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent advances in development of hetero-bivalent kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.66 | 9.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5194339 | — | — | 1 | 9.38 |
| CHEMBL5198165 | — | — | 1 | 6.82 |
| CHEMBL5209851 | — | — | 1 | 6.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5194339 | — | Kd | = | 0.42 | nM | 9.38 |
| CHEMBL5198165 | — | Kd | = | 150.0 | nM | 6.82 |
| CHEMBL5209851 | — | Kd | = | 170.0 | nM | 6.77 |