Assay Detail
Functional
CHEMBL5097616
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Anticancer activity against human Huh-7 cells assessed as inhibition of cell proliferation incubated for 4 days by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
AAA ATPases as therapeutic targets: Structure, functions, and small-molecule inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.28 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34241 | ROTTLERIN | — | 1 | 6.24 |
| CHEMBL258844 | — | — | 1 | 5.40 |
| CHEMBL1085767 | — | — | 1 | 4.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34241 | ROTTLERIN | IC50 | = | 570.0 | nM | 6.24 |
| CHEMBL258844 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1085767 | — | IC50 | = | 63700.0 | nM | 4.20 |