Assay Detail
Functional
CHEMBL5097737
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Antiproliferative activity against human NCI-H1975 assessed as cell growth inhibition
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H1975 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pyrimidine-based EGFR TK inhibitors in targeted cancer therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.90 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4209019 | — | — | 2 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4209019 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL4209019 | — | IC50 | = | 400.0 | nM | 6.40 |