Assay Detail
Functional
CHEMBL5097887
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Antimalarial activity against Plasmodium falciparum NF54
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure activity relationship in β-carboline derived anti-malarial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.78 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1083769 | — | — | 1 | 8.05 |
| CHEMBL1083768 | — | — | 1 | 7.57 |
| CHEMBL1084077 | — | — | 1 | 6.90 |
| CHEMBL1085371 | — | — | 1 | 6.35 |
| CHEMBL1084078 | — | — | 1 | 6.07 |
| CHEMBL1085370 | — | — | 1 | 5.74 |
| CHEMBL1085369 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1083769 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL1083768 | — | IC50 | = | 27.0 | nM | 7.57 |
| CHEMBL1084077 | — | IC50 | = | 126.0 | nM | 6.90 |
| CHEMBL1085371 | — | IC50 | = | 444.0 | nM | 6.35 |
| CHEMBL1084078 | — | IC50 | = | 857.0 | nM | 6.07 |
| CHEMBL1085370 | — | IC50 | = | 1808.0 | nM | 5.74 |
| CHEMBL1085369 | — | IC50 | >= | 5000.0 | nM | - |