Assay Detail

CHEMBL5098256

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Functional

Antiviral activity against Ebola virus

ChEMBL ↗

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Target

Ebolavirus (CHEMBL4434621) ↗

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Primary target Ebolavirus

CHEMBL4434621

Anchored from Assay target.

Protein identity Ebolavirus

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Ebolavirus
Confidence	1 — Organism
Curated By	Autocuration

Target

Ebolavirus (CHEMBL4434621) ↗

Type	ORGANISM
Organism	Ebolavirus

Publication

Potential pharmacological strategies targeting the Niemann-Pick C1 receptor and Ebola virus glycoprotein interaction.

Morales-Tenorio M, Ginex T, Cuesta-Geijo MÁ, Campillo NE, Muñoz-Fontela C, Alonso C, Delgado R, Gil C.
Eur J Med Chem (2021) 223 : 113654 -113654
PubMed 34175537 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.79	6.79

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1655	TOREMIFENE	4.0	1	6.79

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1655	TOREMIFENE	IC50	=	162.0	nM	6.79