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Assay Detail

CHEMBL5104376

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of VEGFR-2 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Vascular endothelial growth factor receptor 2 (CHEMBL279)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Pyridazine as a privileged structure: An updated review on anticancer activity of pyridazine containing bioactive molecules.
He ZX, Gong YP, Zhang X, Ma LY, Zhao W.
Eur J Med Chem (2021) 209 : 112946 -112946
PubMed 33129590 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.64 10.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5189340 1 10.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5189340 IC50 = 0.023 nM 10.64