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Assay Detail

CHEMBL5106702

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Binding
Binding affinity to GID4 (unknown origin) assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glucose-induced degradation protein 4 homolog (CHEMBL5169174)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
Chana CK, Maisonneuve P, Posternak G, Grinberg NGA, Poirson J, Ona SM, Ceccarelli DF, Mader P, St-Cyr DJ, Pau V, Kurinov I, Tang X, Deng D, Cui W, Su W, Kuai L, Soll R, Tyers M, Röst HL, Batey RA, Taipale M, Gingras AC, Sicheri F.
J Med Chem (2022) 65 : 12725 -12746
PubMed 36117290 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.72 5.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5195622 1 5.72

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5195622 Kd = 1900.0 nM 5.72