Compound Detail
CHEMBL5195622
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)C[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)O
Basic Information
| ChEMBL ID | CHEMBL5195622 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NPFAUGYEWVKESQ-AQRCPPRCSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
790.0
MW (Da)
-1.82
ALogP
11
HBA
12
HBD
286.0
PSA (Ų)
0.04
QED
3
Ro5 Violations
23
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 5.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glucose-induced degradation protein 4 homolog CHEMBL5169174 | Kd | 5.72 | 5.72 | 1900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glucose-induced degradation protein 4 homolog | Kd | = | 1900.0 | nM | 5.72 | Binding affinity to GID4 (unknown origin) assessed as dissociation constant | 36117290 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36117290 | 10.1021/acs.jmedchem.2c00509 | Glucose-induced degradation protein 4 homolog | 1 |
Data from ChEMBL 36 via Core Engine