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Assay Detail

CHEMBL5108116

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Functional
Agonist activity at human CB2R expressed in mouse AtT20 cells by FLIPR membrane potential assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type AtT20
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 2 (CHEMBL253)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and antitumour evaluation of indole-2-carboxamides against paediatric brain cancer cells.
Alsayed SSR, Suri A, Bailey AW, Lane S, Werry EL, Huang CC, Yu LF, Kassiou M, Sredni ST, Gunosewoyo H.
RSC Med Chem (2021) 12 : 1910 -1925
PubMed 34825187 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.21 7.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1592888 1 7.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1592888 EC50 = 62.0 nM 7.21