Assay Detail
Binding
CHEMBL5108828
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Displacement of [32P]S1P from human recombinant S1PR3 incubated for 60 mins by competitive binding assay based scintillation counter
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of highly selective quinazoline-2,4-dione ligands for sphingosine-1-phosphate receptor 2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 9.40 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL225155 | — | — | 1 | 9.40 |
| CHEMBL5184621 | — | — | 1 | - |
| CHEMBL5200959 | — | — | 1 | - |
| CHEMBL5178835 | — | — | 1 | - |
| CHEMBL5184379 | — | — | 1 | - |
| CHEMBL5199972 | — | — | 1 | - |
| CHEMBL5192525 | — | — | 1 | - |
| CHEMBL5199020 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL225155 | — | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL5184621 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL5200959 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL5178835 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL5184379 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL5199972 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL5192525 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL5199020 | — | IC50 | > | 1000.0 | nM | - |