Assay Detail
Binding
CHEMBL5110023
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Binding affinity to human recombinant 5-HT1A expressed in CHO cells assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.28 | 8.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5196950 | — | — | 1 | 8.39 |
| CHEMBL5172635 | — | — | 1 | 8.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5196950 | — | Ki | = | 4.1 | nM | 8.39 |
| CHEMBL5172635 | — | Ki | = | 6.8 | nM | 8.17 |