Assay Detail
Binding
CHEMBL5110682
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of EL red from human full-length ER-beta expressed in baculovirus expression system incubated for 2 hrs by fluorescence polarization assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
An overview on Estrogen receptors signaling and its ligands in breast cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.34 | 7.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL424829 | — | — | 1 | 7.24 |
| CHEMBL44 | GENISTEIN | 2.0 | 1 | 7.11 |
| CHEMBL8145 | DAIDZEIN | 2.0 | 1 | 5.76 |
| CHEMBL198877 | AUS-131 | 2.0 | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL424829 | — | IC50 | = | 58.2 | nM | 7.24 |
| CHEMBL44 | GENISTEIN | IC50 | = | 78.0 | nM | 7.11 |
| CHEMBL8145 | DAIDZEIN | IC50 | = | 1738.0 | nM | 5.76 |
| CHEMBL198877 | AUS-131 | IC50 | = | 5571.0 | nM | 5.25 |