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Assay Detail

CHEMBL5111007

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to SHH (unknown origin) assessed as dissociation constant by calorimetric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Sonic hedgehog protein (CHEMBL5602)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Cyclic Peptide Screening Methods for Preclinical Drug Discovery.
Li X, Craven TW, Levine PM.
J Med Chem (2022) 65 : 11913 -11926
PubMed 36074956 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.26 6.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5185285 1 6.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5185285 Kd = 550.0 nM 6.26