Assay Detail
Functional
CHEMBL5113661
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Neuroprotective activity against glutamate-induced mouse primary cortical neurons assessed as neuronal viability incubated for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Cortical neurone |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Paradigm shift of "classical" HDAC inhibitors to "hybrid" HDAC inhibitors in therapeutic interventions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.43 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5205944 | — | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5205944 | — | EC50 | = | 3700.0 | nM | 5.43 |