Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5113789

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]serotonin from recombinant human 5-HT1D receptor expressed in HEK293 cells incubated for 1 hr by competitive radioligand binding assay based
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HEK293
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1D (CHEMBL1983)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Research progress in biological activities of isochroman derivatives.
Zhao Z, Kang K, Yue J, Ji X, Qiao H, Fan P, Zheng X.
Eur J Med Chem (2021) 210 : 113073 -113073
PubMed 33310287 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.05 9.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL71838 1 9.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL71838 Ki = 0.9 nM 9.05