Assay Detail
Functional
CHEMBL5114130
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Antiproliferative activity against human NCI-H460 cells after 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.34 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5190939 | — | — | 1 | 6.34 |
| CHEMBL5197555 | — | — | 1 | 5.24 |
| CHEMBL5202492 | — | — | 1 | 5.02 |
| CHEMBL5182712 | — | — | 1 | 4.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5190939 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL5197555 | — | IC50 | = | 5780.0 | nM | 5.24 |
| CHEMBL5202492 | — | IC50 | = | 9620.0 | nM | 5.02 |
| CHEMBL5182712 | — | IC50 | = | 18100.0 | nM | 4.74 |