Assay Detail
Binding
CHEMBL5114212
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Binding affinity to KA receptor (unknown origin)
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.43 | 4.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5186117 | — | — | 1 | 4.62 |
| CHEMBL5198336 | — | — | 1 | 4.24 |
| CHEMBL5179605 | — | — | 1 | - |
| CHEMBL5187440 | — | — | 1 | - |
| CHEMBL5199355 | — | — | 1 | - |
| CHEMBL1375097 | — | — | 1 | - |
| CHEMBL5195778 | — | — | 1 | - |
| CHEMBL5174264 | — | — | 1 | - |
| CHEMBL5190991 | — | — | 1 | - |
| CHEMBL5208673 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5186117 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL5198336 | — | IC50 | = | 57000.0 | nM | 4.24 |
| CHEMBL5179605 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5187440 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5199355 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1375097 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5195778 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5174264 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5190991 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5208673 | — | IC50 | > | 100000.0 | nM | - |