Assay Detail
Binding
CHEMBL5114213
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Binding affinity to NMDA receptor (unknown origin)
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 4.27 | 4.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5195778 | — | — | 1 | 4.39 |
| CHEMBL1375097 | — | — | 1 | 4.28 |
| CHEMBL5179605 | — | — | 1 | 4.26 |
| CHEMBL5187440 | — | — | 1 | 4.25 |
| CHEMBL5199355 | — | — | 1 | 4.16 |
| CHEMBL5186117 | — | — | 1 | - |
| CHEMBL5174264 | — | — | 1 | - |
| CHEMBL5198336 | — | — | 1 | - |
| CHEMBL5190991 | — | — | 1 | - |
| CHEMBL5208673 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5195778 | — | Ki | = | 41000.0 | nM | 4.39 |
| CHEMBL1375097 | — | Ki | = | 53000.0 | nM | 4.28 |
| CHEMBL5179605 | — | Ki | = | 55000.0 | nM | 4.26 |
| CHEMBL5187440 | — | Ki | = | 56000.0 | nM | 4.25 |
| CHEMBL5199355 | — | Ki | = | 69000.0 | nM | 4.16 |
| CHEMBL5186117 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL5174264 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL5198336 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL5190991 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL5208673 | — | Ki | > | 100000.0 | nM | - |