Assay Detail
Binding
CHEMBL5114490
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse GAT-4 assessed as inhibition of [3H]GABA uptake by liquid scintillation counter method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Nipecotic acid as potential lead molecule for the development of GABA uptake inhibitors; structural insights and design strategies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.24 | 5.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4126078 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4126078 | — | IC50 | = | 5780.0 | nM | 5.24 |