Assay Detail
Binding
CHEMBL5116525
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to mouse STING assessed as dissociation constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Stimulator of interferon genes protein (CHEMBL4523311) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.81 | 6.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL71263 | VADIMEZAN | 3.0 | 1 | 6.15 |
| CHEMBL1569545 | CRIDANIMOD | 3.0 | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL71263 | VADIMEZAN | Kd | = | 710.0 | nM | 6.15 |
| CHEMBL1569545 | CRIDANIMOD | Kd | = | 3500.0 | nM | 5.46 |