Assay Detail
Functional
CHEMBL5124403
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against MERS-CoV by enzymatic assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Middle East respiratory syndrome-related coronavirus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Middle East respiratory syndrome-related coronavirus (CHEMBL4296578) ↗| Type | ORGANISM |
| Organism | Middle East respiratory syndrome-related coronavirus |
Publication
Peptidomimetics: An Overview of Recent Medicinal Chemistry Efforts toward the Discovery of Novel Small Molecule Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 6.82 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5174145 | — | — | 1 | 7.16 |
| CHEMBL5184284 | — | — | 1 | 7.10 |
| CHEMBL5175540 | — | — | 1 | 7.10 |
| CHEMBL5172701 | — | — | 1 | 7.00 |
| CHEMBL5173283 | — | — | 1 | 7.00 |
| CHEMBL5188945 | — | — | 1 | 6.89 |
| CHEMBL5190394 | — | — | 1 | 6.82 |
| CHEMBL5194912 | — | — | 1 | 6.82 |
| CHEMBL5178275 | — | — | 1 | 6.82 |
| CHEMBL5195656 | — | — | 1 | 6.46 |
| CHEMBL2315036 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5174145 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL5184284 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL5175540 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL5172701 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5173283 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5188945 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL5190394 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL5194912 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL5178275 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL5195656 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL2315036 | — | IC50 | = | 1600.0 | nM | 5.80 |