Assay Detail
Functional
CHEMBL5124434
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Antitumor activity against human BT-474 cells assessed as cell growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BT-474 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Peptidomimetics: An Overview of Recent Medicinal Chemistry Efforts toward the Discovery of Novel Small Molecule Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.68 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4749062 | — | — | 1 | 6.50 |
| CHEMBL4753399 | — | — | 1 | 6.21 |
| CHEMBL5174749 | — | — | 1 | 5.57 |
| CHEMBL5173034 | — | — | 1 | 5.16 |
| CHEMBL5186255 | — | — | 1 | 4.97 |
| CHEMBL5201949 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4749062 | — | EC50 | = | 320.0 | nM | 6.50 |
| CHEMBL4753399 | — | EC50 | = | 610.0 | nM | 6.21 |
| CHEMBL5174749 | — | EC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL5173034 | — | EC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL5186255 | — | EC50 | = | 10800.0 | nM | 4.97 |
| CHEMBL5201949 | — | EC50 | - | — | - |