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Assay Detail

CHEMBL5124454

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human BT-20 cells assessed as cell growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type BT-20
Confidence 1 — Organism
Curated By Autocuration

Target

BT-20 (CHEMBL613870)
Type CELL-LINE
Organism Homo sapiens

Publication

Peptidomimetics: An Overview of Recent Medicinal Chemistry Efforts toward the Discovery of Novel Small Molecule Inhibitors.
Li Petri G, Di Martino S, De Rosa M.
J Med Chem (2022) 65 : 7438 -7475
PubMed 35604326 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.60 4.78

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4465565 1 4.78
CHEMBL4561695 1 4.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4465565 IC50 = 16500.0 nM 4.78
CHEMBL4561695 IC50 = 38400.0 nM 4.42