Assay Detail
Functional
CHEMBL5124700
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anti-HIV activity against HIV-1 NL4-3 Nanoluc-sec virus infected in human MT4 cells assessed as luciferase activity and measured 3 days post-infection by Nano-Glo luciferase assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Anti-HIV Tigliane-Type Diterpenoids from the Aerial Parts of <i>Wikstroemia lichiangensis</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.69 | 9.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3741746 | — | — | 1 | 9.82 |
| CHEMBL5176596 | — | — | 1 | 8.96 |
| CHEMBL5194295 | — | — | 1 | 8.82 |
| CHEMBL5205591 | — | — | 1 | 8.82 |
| CHEMBL5174812 | — | — | 1 | 8.52 |
| CHEMBL5200490 | — | — | 1 | 7.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3741746 | — | IC50 | = | 0.15 | nM | 9.82 |
| CHEMBL5176596 | — | IC50 | = | 1.1 | nM | 8.96 |
| CHEMBL5194295 | — | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL5205591 | — | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL5174812 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL5200490 | — | IC50 | = | 65.4 | nM | 7.18 |