Assay Detail
Functional
CHEMBL5126142
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MFM-223 cells assessed as inhibition of cell growth measured after 5 days by cell titer glo-based luminescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MFM-223 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of a Highly Potent and Selective Dual PROTAC Degrader of CDK12 and CDK13.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.33 | 7.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5178057 | — | — | 1 | 7.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5178057 | — | IC50 | = | 47.0 | nM | 7.33 |