Assay Detail
Binding
CHEMBL5127264
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of full-length wild-type BTK (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Review of the development of BTK inhibitors in overcoming the clinical limitations of ibrutinib.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.07 | 9.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4756476 | NEMTABRUTINIB | 3.0 | 1 | 9.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4756476 | NEMTABRUTINIB | IC50 | = | 0.85 | nM | 9.07 |