Assay Detail
Binding
CHEMBL5127778
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of tracer 178 from N-terminal GST-fused human WEE1 (215 to 646 residues) expressed in baculovirus expression system preincubated for 5 mins followed by tracer addition measured after 60 mins by Lantha Screen EU assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent advances in DDR (DNA damage response) inhibitors for cancer therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.99 | 8.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5199347 | — | — | 1 | 8.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5199347 | — | IC50 | = | 1.03 | nM | 8.99 |