Assay Detail
Binding
CHEMBL5127804
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Binding affinity to Androgen receptor (unknown origin) assessed as inhibition constant
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Overview of the development of selective androgen receptor modulators (SARMs) as pharmacological treatment for osteoporosis (1998-2021).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 8.48 | 9.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL469759 | — | — | 1 | 9.27 |
| CHEMBL436784 | — | — | 1 | 9.00 |
| CHEMBL5184779 | — | — | 1 | 8.85 |
| CHEMBL511130 | — | — | 1 | 8.40 |
| CHEMBL4754501 | — | — | 1 | 8.40 |
| CHEMBL125663 | — | — | 1 | 8.22 |
| CHEMBL409 | BICALUTAMIDE | 4.0 | 1 | 7.96 |
| CHEMBL401805 | — | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL469759 | — | Ki | = | 0.54 | nM | 9.27 |
| CHEMBL436784 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL5184779 | — | Ki | = | 1.4 | nM | 8.85 |
| CHEMBL511130 | — | Ki | = | 4.0 | nM | 8.40 |
| CHEMBL4754501 | — | Ki | = | 4.0 | nM | 8.40 |
| CHEMBL125663 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL409 | BICALUTAMIDE | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL401805 | — | Ki | = | 18.0 | nM | 7.75 |