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Assay Detail

CHEMBL5127829

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Functional
Cytotoxicity against human MOLM-14 cells assessed as inhibition of cell growth incubated for 72 hrs by alamar blue assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MOLM-14
Confidence 1 — Organism
Curated By Autocuration

Target

MOLM-14 (CHEMBL3706570)
Type CELL-LINE
Organism Homo sapiens

Publication

Emerging targeted protein degradation tools for innovative drug discovery: From classical PROTACs to the novel and beyond.
Zhong Y, Chi F, Wu H, Liu Y, Xie Z, Huang W, Shi W, Qian H.
Eur J Med Chem (2022) 231 : 114142 -114142
PubMed 35092900 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5195741 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5195741 IC50 = 300.0 nM 6.52