Assay Detail
Binding
CHEMBL5127883
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Binding affinity to EED (unknown origin) assessed as dissociation constant SPR assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent strategies targeting Embryonic Ectoderm Development (EED) for cancer therapy: Allosteric inhibitors, PPI inhibitors, and PROTACs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.19 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL97453 | WEDELOLACTONE | — | 1 | 5.55 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | 3.0 | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL97453 | WEDELOLACTONE | Kd | = | 2820.0 | nM | 5.55 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | Kd | = | 15100.0 | nM | 4.82 |