Assay Detail
Binding
CHEMBL5128226
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Inhibition of AChE (unknown origin) incubated for 30 mins by Ellman's method
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.01 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL502 | DONEPEZIL | 4.0 | 1 | 8.40 |
| CHEMBL659 | GALANTAMINE | 4.0 | 1 | 5.93 |
| CHEMBL5176910 | — | — | 1 | 5.75 |
| CHEMBL5202541 | — | — | 1 | 5.75 |
| CHEMBL5196941 | — | — | 1 | 5.75 |
| CHEMBL5197349 | — | — | 1 | 5.75 |
| CHEMBL5185240 | — | — | 1 | 5.75 |
| CHEMBL5169638 | — | — | 1 | 5.75 |
| CHEMBL5200035 | — | — | 1 | 5.75 |
| CHEMBL5182136 | — | — | 1 | 5.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL502 | DONEPEZIL | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL659 | GALANTAMINE | IC50 | = | 1170.0 | nM | 5.93 |
| CHEMBL5176910 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL5202541 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL5196941 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL5197349 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL5185240 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL5169638 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL5200035 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL5182136 | — | IC50 | = | 2800.0 | nM | 5.55 |