Assay Detail
Binding
CHEMBL5128227
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of BChE (unknown origin) incubated for 30 mins by Ellman's method
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.46 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL659 | GALANTAMINE | 4.0 | 1 | 5.70 |
| CHEMBL502 | DONEPEZIL | 4.0 | 1 | 5.50 |
| CHEMBL5176910 | — | — | 1 | 5.46 |
| CHEMBL5202541 | — | — | 1 | 5.46 |
| CHEMBL5196941 | — | — | 1 | 5.46 |
| CHEMBL5197349 | — | — | 1 | 5.46 |
| CHEMBL5185240 | — | — | 1 | 5.46 |
| CHEMBL5169638 | — | — | 1 | 5.46 |
| CHEMBL5200035 | — | — | 1 | 5.46 |
| CHEMBL5182136 | — | — | 1 | 5.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL659 | GALANTAMINE | IC50 | = | 2015.0 | nM | 5.70 |
| CHEMBL502 | DONEPEZIL | IC50 | = | 3130.0 | nM | 5.50 |
| CHEMBL5176910 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL5202541 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL5196941 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL5197349 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL5185240 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL5169638 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL5200035 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL5182136 | — | IC50 | = | 6300.0 | nM | 5.20 |