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Assay Detail

CHEMBL5128229

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of cox-2 (unknown origin) incubated for 5 mins by 96-well plate method
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cytochrome c oxidase subunit 2 (CHEMBL6174)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy.
Fantacuzzi M, Amoroso R, Carradori S, De Filippis B.
Eur J Med Chem (2022) 233 : 114242 -114242
PubMed 35276424 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 8 5.07 5.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5182136 1 5.07
CHEMBL5176910 1 5.07
CHEMBL5202541 1 5.07
CHEMBL5196941 1 5.07
CHEMBL5197349 1 5.07
CHEMBL5185240 1 5.07
CHEMBL5169638 1 5.07
CHEMBL5200035 1 5.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5182136 IC50 = 8600.0 nM 5.07
CHEMBL5176910 IC50 = 8600.0 nM 5.07
CHEMBL5202541 IC50 = 8600.0 nM 5.07
CHEMBL5196941 IC50 = 8600.0 nM 5.07
CHEMBL5197349 IC50 = 8600.0 nM 5.07
CHEMBL5185240 IC50 = 8600.0 nM 5.07
CHEMBL5169638 IC50 = 8600.0 nM 5.07
CHEMBL5200035 IC50 = 8600.0 nM 5.07