Assay Detail
Functional
CHEMBL5128259
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Cytotoxicity against human HCT-116 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent applications of vinyl sulfone motif in drug design and discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.76 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2013119 | RIGOSERTIB SODIUM | 3.0 | 1 | 8.00 |
| CHEMBL5178200 | — | — | 1 | 4.74 |
| CHEMBL5178262 | — | — | 1 | 4.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2013119 | RIGOSERTIB SODIUM | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5178200 | — | IC50 | = | 18100.0 | nM | 4.74 |
| CHEMBL5178262 | — | IC50 | = | 29300.0 | nM | 4.53 |